S-Adenosyl-L-methionine in a Neuroblastoma
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چکیده
منابع مشابه
A cDNA encoding S-adenosyl-L-methionine synthetase from poplar.
Adomet synthetase (EC 2.5.1.6) catalyzes the formation of Adomet, which serves as a methyl group donor in highly specific transmethylation reactions involving a11 kinds of acceptor molecules such as proteins, nucleic acids, phenylpropanoid derivatives, polysaccharides, cyclic fatty acids, etc. Adomet also plays a role in amino acid biosynthesis and polyamine biosynthesis. In plants, Adomet has ...
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UNLABELLED S-Adenosyl-L-homocysteine, the product of S-adenosyl-L-methionine (SAM) methyltransferases, is known to be a strong feedback inhibitor of these enzymes. A hydrolase specific for S-adenosyl-L-homocysteine produces L-homocysteine, which is remethylated to methionine and can be used to regenerate SAM. Here, we show that the annotated S-adenosyl-L-homocysteine hydrolase in Methanocaldoco...
متن کاملPurification of rat liver S-adenosyl-L-methionine decarboxylase.
The amount of S-adenosyl-l-methionine decarboxylase present in rat liver was enhanced 17-fold by administration of methylglyoxal bis(guanylhydrazone),* a specific inhibitor of the enzyme. The enzyme was purified 1400-fold in 50% yield from such liver extracts by chromatography on columns of the inhibitor bound to Sepharose. The purified enzyme had no spermidine synthetase activity.
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Furanocoumarins, Phytoalexins, O-Methyltransferases, Fungal Elicitor, Cell Suspension Cultures Cultured parsley cells (Petroselinum crispum) treated with an elicitor from the soybean patho gen, Phytophthora megasperma f. sp. glycinea, were used as source for the separation, extensive purification and characterization of S-adenosyl-L-methionine: xanthotoxol and S-adenosyl-Lmethionine: bergaptol...
متن کاملTumor uptake studies of S-adenosyl-L-[methyl-11C]methionine and L-[methyl-11C]methionine.
Tumor accumulation of S-adenosyl-L-[methyl-11C]methionine ([11C]SAM) was investigated in mice bearing mammary carcinoma (FM3A) and in rats bearing ascitic hepatoma (AH109A). After injection of [11C]SAM the blood clearance of 11C radioactivity was rapid. The 11C level was relatively high in both tumors. The uptake ratios of tumor to organ increased with time in several organs, especially in brai...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1970
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197009000-00082